Cardiology

Estimated Plasma Volume Status (ePVS)

Quantifies intravascular plasma volume and congestion in heart failure.

Parameters

%

Estimated Plasma Volume Status (ePVS) Result

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FormulaePV (mL) = (1 - Hct) × [a + (b × Weight)] Males: a=1530, b=41.0; Females: a=864, b=47.9 ePVS (%) = [(Actual ePV - Ideal ePV) / Ideal ePV] × 100

Clinical Pearls

A non-invasive metric to monitor decongestion and optimize discharge timing in acute decompensated heart failure patients.

Limitations

Assumes normal red blood cell mass; chronic severe anemia or polycythemia can distort the relationship between hematocrit and plasma volume.