Critical Care
Oxygen Content (CaO₂) & Oxygen Delivery (DO₂ / DO₂I) Calculator
Calculates arterial oxygen content (CaO₂), global oxygen delivery (DO₂), and indexed DO₂I to detect tissue dysoxia.
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Parameters
Oxygen Content (CaO₂) & Oxygen Delivery (DO₂ / DO₂I) Calculator Result
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Formula
CaO₂ (mL/dL) = [1.34 × Hb (g/dL) × (SaO₂ / 100)] + [0.0031 × PaO₂ (mmHg)]
DO₂ (mL/min) = Cardiac Output (L/min) × CaO₂ (mL/dL) × 10 (Normal: 900–1100 mL/min)
DO₂I (mL/min/m²) = Cardiac Index (L/min/m²) × CaO₂ × 10 (Normal: 500–600 mL/min/m²)Clinical Pearls
Underpins goal-directed resuscitation in septic shock, cardiogenic shock, and major trauma surgery by balancing the three determinants of cellular oxygenation: hemoglobin, oxygenation, and cardiac output.
Limitations
Assumes standard oxygen-binding capacity of hemoglobin (1.34 mL O₂/g Hb); carbon monoxide (carboxyhemoglobin) and methemoglobin falsely elevate measured SaO₂ on standard pulse oximeters.