General
Albumin-to-Globulin (A/G) Ratio
Calculates calculated globulin and A/G ratio for liver, renal, and myeloma workups.
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Parameters
Albumin-to-Globulin (A/G) Ratio Result
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Formula
Calculated Globulin (g/dL) = Total Protein - Serum Albumin
A/G Ratio = Serum Albumin / Calculated GlobulinClinical Pearls
A cornerstone lab screen for unexplained hyperproteinemia, guiding the detection of occult plasma cell dyscrasias and chronic inflammatory states.
Limitations
Calculated globulin encompasses alpha-1, alpha-2, beta, and gamma globulin fractions; serum protein electrophoresis (SPEP) is required to pinpoint specific immunoglobulin elevations.