Oncology

MASCC Risk Index for Febrile Neutropenia

Stratifies cancer patients with febrile neutropenia into low- vs high-risk for severe complications.

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Parameters

MASCC Risk Index for Febrile Neutropenia Result

Formula

MASCC Score (0-26) = Symptom burden (0/3/5) + No Hypotension (5) + No COPD (4) + Solid Tumor (4) + No Dehydration (3) + Outpatient (3) + Age <60 (2)

Clinical Pearls

Empowers oncologists and emergency physicians to safely select appropriate candidates for outpatient oral antimicrobial therapy versus urgent inpatient IV therapy.

Limitations

Not applicable to pediatric cancer patients; clinical judgment supersedes score if severe localized infection, hemodynamic compromise, or poor social support is present.