Back to All Courses
100% Free Video Course
USMLE Step 1

Boards and Beyond USMLE Step 1 2025

Comprehensive video lectures covering all USMLE Step 1 topics. Dr. Jason Ryan explains complex basic science concepts with clinical correlations, making high-yield material easy to understand and retain.

419 Video Lectures 21 Chapters Self-Paced Streaming
Instant Free Access: All video lectures are free to watch on-demand.
Pro Ad-Free Option

Course Curriculum & Video Lectures

Select any lecture below to stream directly.

Course Chapters (21)

|
1

Pharmacology

5 lectures

General Topics - Dose-Response

General Topics - Enzyme Inhibitors

General Topics - Drug Elimination

General Topics - Enzymes

General Topics - Pharmacokinetics

2

Behavioral Science

9 lectures

General Topics - Confidentiality

General Topics - Decision-Making Capacity

General Topics - Ethics Principles

General Topics - Geriatrics

General Topics - Informed Consent

General Topics - Pediatrics

General Topics - Public Health

General Topics - Quality and Safety

General Topics - The Healthy Patient

3

Biochemistry

28 lectures

Amino Acids - Amino Acids

Amino Acids - Ammonia

Amino Acids - Other Amino Acids

Amino Acids - Phenylalanine and Tyrosine

Lipids - Hyperlipidemia

Lipids - Lipid Drugs

Lipids - Lipid Metabolism

Metabolism - Electron Transport Chain

Metabolism - Ethanol Metabolism

Metabolism - Exercise and Starvation

Metabolism - Fatty Acids

Metabolism - Fructose and Galactose

Metabolism - Gluconeogenesis

Metabolism - Glucose

Metabolism - Glycogen

Metabolism - Glycolysis

Metabolism - HMP Shunt

Metabolism - Inborn Errors of Metabolism

Metabolism - Ketone Bodies

Metabolism - Pyruvate Dehydrogenase

Metabolism - TCA Cycle

Molecular Biochemistry - DNA Structure

Molecular Biochemistry - Purine Metabolism

Molecular Biochemistry - Pyrimidine Metabolism

Other Topics - Lysosomal Storage Diseases

Vitamins - B Vitamins

Vitamins - B12 and Folate

Vitamins - Other Vitamins

4

Biostats-Epi

12 lectures

Biostatistics - Correlations

Biostatistics - Hypothesis Testing

Biostatistics - Statistics

Biostatistics - Tests of Significance

Epidemiology - Bias

Epidemiology - Clinical Trials

Epidemiology - Diagnostic Tests

Epidemiology - Evidence-based Medicine

Epidemiology - Predictive Values

Epidemiology - Risk Quantification

Epidemiology - Sensitivity and Specificity

Epidemiology - Study Designs

5

Cardiology

43 lectures

Anatomy and Physiology - Blood Flow Mechanics

Anatomy and Physiology - Cardiac Anatomy

Anatomy and Physiology - Cardiac Physiology

Anatomy and Physiology - CV Response to Exercise

Anatomy and Physiology - PV Loops

Anatomy and Physiology - Regulation of Blood Pressure

Anatomy and Physiology - Starling Curve

Anatomy and Physiology - Venous Pressure Tracings

Anatomy and Physiology - Wiggers Diagram

Arrhythmias - Antiarrhythmic Drugs

Arrhythmias - Atrial Fibrillation and Flutter

Arrhythmias - AV and Bundle Branch Blocks

Arrhythmias - AVNRT

Arrhythmias - Cardiac Action Potentials

Arrhythmias - WPW

Cardiac Auscultation - Heart Murmurs

Cardiac Auscultation - Heart Sounds

Cardiac Ischemia - Atherosclerosis

Cardiac Ischemia - Cardiac Ischemia

Cardiac Ischemia - Stable Angina

Cardiac Ischemia - STEMI

Cardiac Ischemia - Unstable Angina NSTEMI

EKGs - EKG Basics

EKGs - High Yield EKGs

Heart Failure - Acute Heart Failure

Heart Failure - Chronic Heart Failure

Heart Failure - Heart Failure Basics

Heart Failure - Restrictive Cardiomyopathy

Heart Failure - Systolic and Diastolic Heart Failure

Hypertension - Hypertension Drugs

Hypertension - Hypertension

Hypertension - Secondary Hypertension

Other Cardiovascular Topics - Aortic Dissection

Other Cardiovascular Topics - Cardiac Tumors

Other Cardiovascular Topics - Endocarditis

090 Other Cardiovascular Topics Hypertrophic Cardiomyopathy

Other Cardiovascular Topics - Pericardial Disease

Other Cardiovascular Topics - Shock

Other Cardiovascular Topics - Valve Disease

The Developing Heart - Cardiac Embryology

The Developing Heart - Coarctation of the Aorta

096 The Developing Heart Cyanotic Congenital Heart Disease

The Developing Heart - Shunts

6

Cell Biology

13 lectures

Cellular Biology - Cell Cycle

Cellular Biology - Cell Structure

Cellular Biology - Connective Tissue

Cellular Biology - Cytoskeleton

Laboratory Techniques - Blotting

Laboratory Techniques - ELISA

Laboratory Techniques - Microarrays and FISH

Laboratory Techniques - PCR

Molecular Biology - DNA Mutations

Molecular Biology - DNA Repair

Molecular Biology - DNA Replication

Molecular Biology - Transcription

Molecular Biology - Translation

7

Dermatology

12 lectures

General Topics - Blistering Disorders

General Topics - Epithelial Cells

Laboratory Techniques - Flow Cytometry

General Topics - Hypersensitivity Disorders

General Topics - Neurocutaneous Disorders

General Topics - Pigment Disorders

General Topics - Skin Cancer

General Topics - Skin Disorders I

General Topics - Skin Disorders II

General Topics - Skin Infections

General Topics - Skin

General Topics - Vascular Lesions

8

Endocrine

18 lectures

Adrenals - Adrenal Disorders

Adrenals - Adrenal Glands

Adrenals - Congenital Adrenal Hyperplasia

Other Topics - MEN Syndromes

Other Topics - Parathyroid Glands

Other Topics - Pituitary Gland

Other Topics - Signalling Pathways

Pancreas - Diabetes

Pancreas - Endocrine Pancreas

Pancreas - Insulin

Pancreas - Treatment of Diabetes

Reproductive - Female Reproductive Hormones

Reproductive - Male Reproductive Hormones

Reproductive - Menstrual Cycle

Reproductive - Reproductive Hormones

Thyroid - Thyroid Cancer

Thyroid - Thyroid Disorders

Thyroid - Thyroid Gland

9

Gastroenterology

28 lectures

Anatomy - Gastrointestinal Anatomy

Anatomy - Gastrointestinal Blood Supply

Anatomy - Gastrointestinal Embryology

Anatomy - Gastrointestinal Tract

Anatomy - Hernias

Anatomy - Liver Gallbladder and Pancreas

Anatomy - Salivary Glands

Clinical Gastroenterology - Acute Pancreatitis

Clinical Gastroenterology - Biliary Disorders

Clinical Gastroenterology - Carcinoid Tumors

151 Clinical Gastroenterology Chronic Pancreatitis Pancreatic

Clinical Gastroenterology - Cirrhosis

Clinical Gastroenterology - Colon Cancer

Clinical Gastroenterology - Gallstones

Clinical Gastroenterology - Esophageal Disorders

Clinical Gastroenterology - Gastric Disorders

157 Clinical Gastroenterology Gastrointestinal Pharmacology

Clinical Gastroenterology - Inflammatory Bowel Disease

Clinical Gastroenterology - Intestinal Disorders

Clinical Gastroenterology - Liver Disease

Clinical Gastroenterology - Liver Tumors

Clinical Gastroenterology - Malabsorption

163 Clinical Gastroenterology Wilson s Disease and Hemochromatosis

GI Physiology - Bile

GI Physiology - Bilirubin

GI Physiology - Exocrine Pancreas

GI Physiology - Gastrointestinal Hormones

GI Physiology - Gastrointestinal Secretions

10

Genetics

12 lectures

Genetic Concepts - Gene Mapping

Genetic Concepts - Genetic Principles

Genetic Concepts - Hardy-Weinberg Law

Genetic Concepts - Pedigrees

Genetic Concepts - Imprinting

Genetic Concepts - Meiosis

Genetic Disorders - Deletion Syndromes

Genetic Disorders - Down Syndrome

Genetic Disorders - Muscular Dystrophy

Genetic Disorders - Trinucleotide Repeat Disorders

Genetic Disorders - Trisomy Disorders

Genetic Disorders - Turner and Klinefelter Syndromes

11

Hematology

29 lectures

Cancer Drugs - Alkylating Agents

Cancer Drugs - Antimetabolites

Cancer Drugs - Antitumor Antibiotics

Cancer Drugs - DNA Drugs

Cancer Drugs - Microtubule Inhibitors

Cancer Drugs - Other Cancer Drugs

Hemostasis - Anticoagulant Drugs

Hemostasis - Antiplatelet Drugs

Hemostasis - Coagulation

Hemostasis - Coagulopathies

Hemostasis - Hypercoagulable States

Hemostasis - Platelet Activation

Hemostasis - Platelet Disorders

Other Topics - Porphyrias

Red Blood Cells - Blood Groups

Red Blood Cells - Extrinsic Hemolysis

Red Blood Cells - Hemolysis Basics

Red Blood Cells - Intrinsic Hemolysis

Red Blood Cells - Microcytic Anemias

Red Blood Cells - Other Anemias

Red Blood Cells - Sickle Cell Anemia

Red Blood Cells - Thalassemias

White Blood Cells - Acute Leukemia

White Blood Cells - Amyloidosis

White Blood Cells - Chronic Leukemia

White Blood Cells - Hodgkin Lymphoma

White Blood Cells - Myeloproliferative Disorders

White Blood Cells - Non-Hodgkin Lymphoma

White Blood Cells - Plasma Cell Disorders

12

Immunology

15 lectures

Autoimmune Disorders - Rheumatoid Arthritis

Autoimmune Disorders - Scleroderma

Autoimmune Disorders - Sjogren s Syndrome

Autoimmune Disorders - Systemic Lupus Erythematosus

Autoimmune Disorders - Vasculitis

Basic Immunology - B-cells

Basic Immunology - Innate Immunity

Basic Immunology - Lymph Nodes and Spleen

Basic Immunology - T-cells

Basic Immunology - The Complement System

Clinical Immunology - Hypersensitivity

Clinical Immunology - Immune Deficiency Syndromes

Clinical Immunology - Transplants

Pharmacology - Glucocorticoids and NSAIDs

Pharmacology - Immunosuppressive Drugs

13

Infectious Disease

35 lectures

Antibiotics - Beta Lactams

Antibiotics - Other Antibiotics

Antibiotics - Penicillins

Antibiotics - Protein Synthesis Inhibitors

Antibiotics - Sulfonamides

Bacteria - Gram Negative Rods

Bacteria - Mycobacteria

Bacteria - Other Gram Negatives

Bacteria - Other Gram Positives

Bacteria - Spirochetes

Bacteria - Staphylococci

Bacteria - Streptococci

Bacteria - Zoonotic Infections

Basics of Microbiology - Bacteria

Basics of Microbiology - Bacterial Culture

Basics of Microbiology - Bacterial Identification

Basics of Microbiology - Growth and Genetics

Basics of Microbiology - Shapes and Stains

Basics of Microbiology - Special Growth Requirements

Basics of Microbiology - Virulence

Fungi - Antifungal Drugs

Fungi - Fungal Pneumonias

Fungi - Fungal Skin Infections

Fungi - Opportunistic Fungal Infections

Parasites and Helminths - Helminths

Parasites and Helminths - Malaria

Parasites and Helminths - Protozoa

Viruses - Antiviral Drugs

Viruses - DNA Viruses

Viruses - Herpes Viruses

Viruses - HIV Drugs

Viruses - HIV

Viruses - RNA Viruses

Viruses - Viral Hepatitis

Viruses - Virus Structure

14

Musculoskeletal

23 lectures

Anatomy and Orthopedics - Brachial Plexus

Anatomy and Orthopedics - Hand

Anatomy and Orthopedics - Hip

Anatomy and Orthopedics - Lumbar Radiculopathy

Anatomy and Orthopedics - Knee

Anatomy and Orthopedics - Lumbosacral Plexus

Anatomy and Orthopedics - Shoulder and Elbow

Anatomy and Orthopedics - Wrist

Cell Biology - Bone

Cell Biology - Cardiac Muscle

Cell Biology - Skeletal Muscle

Cell Biology - Smooth Muscle

Pathology - Bone Disorders

Pathology - Bone Tumors

Pathology - CPPD

Pathology - Gout Drugs

Pathology - Gout

Pathology - Muscle Disorders

Pathology - Neuromuscular Disorders

Pathology - Osteoarthritis

Pathology - Osteoporosis Drugs

Pathology - Osteoporosis

Pathology - Seronegative Spondyloarthritis

15

Anesthesia

3 lectures

Anesthesia - General Anesthesia

Anesthesia - Local Anesthesia

Anesthesia - Neuromuscular Blockers

16

Neurology

41 lectures

Autonomic Nervous System - ANS Drugs Acetylcholine

Autonomic Nervous System - ANS Drugs Norepinephrine

Autonomic Nervous System - Autonomic Nervous System

Autonomic Nervous System - Autonomic Receptors

Introduction to Neurology - Blood Brain Barrier

291 Introduction to Neurology Cells of the Nervous System

Introduction to Neurology - Dermatomes and Reflexes

Introduction to Neurology - Nerve Damage

Introduction to Neurology - Neurotransmitters

Nervous System Structures - Auditory System

Nervous System Structures - Basal Ganglia

Nervous System Structures - Brainstem

Nervous System Structures - Cerebral Cortex

Nervous System Structures - Cranial Nerves

Nervous System Structures - Spinal Cord Syndromes

Nervous System Structures - Spinal Cord

303 Nervous System Structures Thalamus Hypothalamus Limbic System

Nervous System Structures - Ventricles and Sinuses

Nervous System Structures - Vestibular System

Neurovascular Disorders - Cerebral and Lacunar Strokes

Neurovascular Disorders - CNS Aneurysms

Neurovascular Disorders - Intracranial Bleeding

Neurovascular Disorders - Management of TIA Stroke

310 Neurovascular Disorders Vertebrobasilar Stroke Syndromes

Other Neurology Topics - Brain Tumors

Other Neurology Topics - Delirium and Dementia

Other Neurology Topics - Headaches

Other Neurology Topics - HIV CNS Infections

Other Neurology Topics - Meningitis

318 Other Neurology Topics Parkinson s Huntington s and Movement

Other Neurology Topics - Neuroembryology

Other Neurology Topics - Seizures

The Eye - Eye Movements

The Eye - Gaze Palsies

The Eye - Glaucoma

Other Neurology Topics - Demyelinating Diseases

The Eye - Structural Eye Disorders

The Eye - The Lens

The Eye - The Pupil

The Eye - The Retina

The Eye - Visual Fields

17

Pathology

11 lectures

General Topics - Acute and Chronic Inflammation

General Topics - Apoptosis

General Topics - Cell Injury

General Topics - Cellular Adaptations

General Topics - Free Radicals

General Topics - Granulomatous Inflammation

General Topics - Inflammation Principles

General Topics - Necrosis

General Topics - Neoplasia

General Topics - Pathologic Calcification

General Topics - Wound Healing and Scar

18

Psychiatry

23 lectures

Pathology - ADHD and Autism

Pathology - Anxiety Disorders

Pathology - Child Abuse and Neglect

Pathology - Childhood Disorders

Pathology - Cognitive Disorders

Pathology - Dissociative Disorders

Pathology - Eating Disorders

Pathology - Mood Disorders

Pathology - Personality Disorders

Pathology - Psychosis

Pathology - Psychotic Disorders

Pathology - Sleep Disorders

Nervous System Structures - Cerebellum

Pathology - Somatic and Factitious Disorders

Pharmacology - Antipsychotics

Pharmacology - Antidepressants

Pharmacology - Lithium

Psychology - Conditioning and Transference

Psychology - Ego Defenses

Substance Use Disorders - Alcohol and CNS Depressants

Substance Use Disorders - Opioids

Substance Use Disorders - Other Drugs

Substance Use Disorders - Stimulants

19

Pulmonary

22 lectures

Embryology Anatomy and Physiology - Carbon Dioxide

Embryology Anatomy and Physiology - Hemoglobin

Embryology Anatomy and Physiology - Hypoxia

Embryology Anatomy and Physiology - Pulmonary Anatomy

365 Embryology Anatomy and Physiology Pulmonary Circulation

366 Embryology Anatomy and Physiology Pulmonary Embryology

367 Embryology Anatomy and Physiology Pulmonary Physical Exam

368 Embryology Anatomy and Physiology Pulmonary Physiology

369 Embryology Anatomy and Physiology Ventilation and Perfusion

370 Obstructive and Restrictive Diseases Obstructive Lung Disease

371 Obstructive and Restrictive Diseases Pulmonary Function Tests

372 Obstructive and Restrictive Diseases Restrictive Lung Disease

373 Obstructive and Restrictive Diseases Treatment of COPD and Asthma

Other Pulmonary Topics - Chest x-rays

Other Pulmonary Topics - Cystic Fibrosis

Other Pulmonary Topics - Lung Cancer

Other Pulmonary Topics - Pleural Disease

Other Pulmonary Topics - Pneumonia

Other Pulmonary Topics - Pulmonary Embolism

Other Pulmonary Topics - Sleep Apnea

Other Pulmonary Topics - Sarcoidosis

Other Pulmonary Topics - Tuberculosis

20

Renal

28 lectures

Acid-Base - Acid Base Problems

Acid-Base - Acid Excretion

Acid-Base - Acid-Base Principles

Acid-Base - Metabolic Acidosis

Acid-Base - Metabolic Alkalosis

Acid-Base - Renal Tubular Acidosis

Acid-Base - Respiratory Acid-Base Disorders

390 Diseases of the Nephron Glomerulonephritis Principles

Diseases of the Nephron - MPGN

Diseases of the Nephron - Nephritic Syndrome

Diseases of the Nephron - Nephrotic Syndrome

Diseases of the Nephron - Renal Failure

Diseases of the Nephron - Tubulointerstitial Disease

Electrolytes - Electrolyte Disorders

Electrolytes - Sodium and Water Balance

Electrolytes - Sodium Disorders

399 Embryology Anatomy and Physiology Nephron Physiology

Embryology Anatomy and Physiology - Renal Anatomy

Embryology Anatomy and Physiology - Renal Embryology

402 Embryology Anatomy and Physiology Renal Endocrinology

403 Embryology Anatomy and Physiology Renal Physiology I

404 Embryology Anatomy and Physiology Renal Physiology II

Other Renal Topics - Cystic Kidney Disease

Other Renal Topics - Diuretics

Other Renal Topics - Kidney stones

Other Renal Topics - Renal and Bladder Tumors

Other Renal Topics - Rhabdomyolysis

Other Renal Topics - Urinary Tract Infections

21

Reproductive

9 lectures

Breast - Breast Carcinoma

Breast - Breast Disorders

Breast - Breast Tissue

Embryology - Cleft Lip and Palate

Embryology - Embryogenesis

Embryology - Embryonic Genes

Embryology - Errors in Morphogenesis

Embryology - Genital Embryology

Embryology - Germ Layers

Advertisement

Topics Covered in This Course

Biochemistry
Physiology
Pharmacology
Pathology
Microbiology
Immunology
Anatomy
Behavioral Science

High-Yield Preparation Strategy

Comprehensive video lectures covering all USMLE Step 1 topics. Dr. Jason Ryan explains complex basic science concepts with clinical correlations, making high-yield material easy to understand and retain.

This curriculum is aligned with licensing exam blueprints for DHA, SMLE, HAAD, MOH, and USMLE Steps 1 & 2 CK. Every video breaks down complex physiological pathways, pathology mechanisms, and pharmacotherapy guidelines into high-yield, testable facts.

Course Overview

100% Free
Total Lectures419
Chapters21
Exam TargetUSMLE Step 1
AccessFree Streaming
Progress SavingFree with Account

Features Included

Free: Full video lecture streaming
Free: Save watch history (with account)
Pro: 100% Ad-Free instant stream
Pro: 50,000+ Prometric & USMLE MCQs
Sponsored Content
Advertisement
Sponsored Content