Pulmonology

Pulmonary Embolism Severity Index (PESI)

Stratifies 30-day mortality risk in acute pulmonary embolism.

Parameters

years

Pulmonary Embolism Severity Index (PESI) Result

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FormulaPESI = Age + [Male:+10] + [Cancer:+30] + [CHF:+10] + [COPD:+10] + [HR≥110:+20] + [SBP<100:+30] + [RR≥30:+20] + [Temp<36°C:+20] + [AMS:+60] + [SpO₂<90%:+20]

Clinical Pearls

Empowers clinicians to safely identify low-risk PE patients who can be treated at home with direct oral anticoagulants (DOACs), avoiding unnecessary hospitalizations.

Limitations

Does not integrate echocardiographic or CT parameters of right ventricular strain or cardiac biomarkers directly.