GastroenterologyIntermediate

MELD-Na Score

Predicts 90-day survival in patients with advanced liver disease.

Clinical Parameters

5 Variables
mg/dL
mg/dL
mEq/L

Awaiting Clinical Parameters

Configure the patient variables on the left and select Calculate Result to generate the clinical score and stratification.

Verified 2026 GuidelinesInstant Calculation
Jump to Formula & Clinical Protocol ↓
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High Yield Prometric TopicGastroenterology & Hepatology

Tested on Gulf Medical Boards (DHA, SMLE, MOH & HAAD)

Clinical calculations and diagnostic scoring systems like MELD-Na Score frequently appear on Prometric exams. Master high-yield clinical vignettes with instant AI-powered pathophysiology rationales.

Clinical Significance & Diagnostic Standard
2026 Clinical Reference

What is the MELD-Na Score?

📋Clinical Summary & Definition Capsule

The MELD-Na Score is an evidence-based clinical decision rule engineered to quantify diagnostic probability, stratify clinical severity, and guide therapeutic decision-making in gastroenterology & hepatology practice. The Model for End-Stage Liver Disease (MELD) incorporates serum sodium (MELD-Na) to better predict 90-day mortality in patients with cirrhosis. It is the standard scoring system used by UNOS for prioritizing liver transplant allocation. Clinical scoring tools like MELD-Na Score are essential in acute and outpatient management, enabling clinicians to objectively differentiate between low-risk candidates suitable for conservative therapy and high-risk patients requiring urgent interventions. Verified against current 2026 clinical standards, this tool is extensively tested on Gulf health authority licensing exams including DHA (Dubai), SMLE (Saudi Arabia), MOH, HAAD/DOH (Abu Dhabi), OMSB (Oman), and QCHP (Qatar).

💡Clinical Pearls & Diagnostic Utility

MELD-Na is the standard metric used by UNOS for the prioritization of patients awaiting liver transplantation in the USA. Higher scores equal higher priority.

Mathematical Formulation

Formula & Calculation Parameters

The mathematical equation and clinical variables required to calculate MELD-Na Score:

MELD = 10 × (0.957 × ln(Cr) + 0.378 × ln(Bili) + 1.120 × ln(INR) + 0.643)
If MELD > 11: MELD-Na = MELD + 1.32(137-Na) - [0.033 × MELD × (137-Na)]
Risk Stratification

Score Interpretation & Clinical Stratification

Score RangeClinical InterpretationRisk Tier
≤ 9Low Risk (<2% 90-day mortality)green
10 – 19Moderate Riskyellow
20 – 29High Risk (20-50% mortality)orange
≥ 30Very High Risk (>50% mortality)red
Clinical Limitations & Contraindications

When to Exercise Caution

Calculations can fluctuate rapidly with changes in creatinine or sodium (e.g. from over-diuresis). It is not designed to predict post-transplant survival, only waitlist mortality.

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Medical Review & Guidelines Compliance
MD

Clinical Review Board

Dr. Muhammad Nouman, MBBS

Capital Medical University | PMDC Reg No: 117744-P

Clinical Audit Status

✓ Verified for 2026 Guidelines

Last updated: 2026-08-07

Peer-Reviewed Medical Literature

  • Biggins SW, Kim WR, Terrault NA, et al. Evidence-based incorporation of serum sodium concentration into MELD. Gastroenterology. 2006;130(6):1652-1660.
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