Nephrology

Hypernatremia Correction Rate (Adrogué-Madias)

Calculates the expected change in serum sodium per liter of IV fluid.

Parameters

years
mEq/L

Hypernatremia Correction Rate (Adrogué-Madias) Result

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FormulaChange in Na = (Infusate Na - Serum Na) / (TBW + 1)

Clinical Pearls

Allows exact prescription of IV fluid rates to achieve a safe target sodium correction rate (usually < 10 mEq/L/day).

Limitations

Does not account for ongoing sensible and insensible fluid/sodium losses. Frequent laboratory monitoring is still required.